Enhance CHITOSAN derivative for dietary supplement (N-acetyl Glucosamine and D-Glucosamine, L112 specification). A non-digestible polysaccharide derived from the deacetylation (removal of the carbonyl and methyl group) of CHITIN blended with additional proprietary ingredients.
It is a refined β 1 → 4 linked co-polymers of N-acetyl Glucosamine and D-glucosamine. The product is a soft yellow powder with a mild fish taste and aroma; and is easy to encapsulate / tableting. And the important properties are fat Triglyceride binding more than 1000 g/g (our standard test method STM-1510) and bulk density more than 0.55 gram per cc
Product Name : L112 BIOPOLYMER
ACTIVE INGREDIENTS : CHITOSAN spec L112 blended with active ingredients
APPEARANCE : soft yellow to beige powder
PACKAGING : L112 BIOPOLYMER is available packed in a 30 kg plastic bag packed in fiber drum
STABILITY : When properly stored the product has a three years shelf life
STORAGE AND HANDLING : Product should be stored in a cool dry place between 5 to 25°C (41-77° F)
SOLUBILITY : Insoluble in water; soluble in weak, organic acids
APPLICATION : L112 BIOPOLYMER Bulk Powder can be used as a dietary supplement To reduce calorie intake from dietary fats, help reduce excess weight and long-term weight control, to lower LDL cholesterol levels and reduce triglycerides fat.
L112 BIOPOLYMER reference
Rossner S, Abelin J:
MATS Medical AB, Stockholm, Sweden, 1995. Abstract: L112 Biopolymer (L112 Fat Blocker) is an investigational drug extracted from shellfish.
L112 Biopolymer has unique properities in its ability of binding fat from the food in the stomach and in the intestines. This leads to a correction and normalization of the LDL cholesterol and triglyceride levels in the blood. The HDL-cholesterol level in the blood increases. The fat sucked out of the food and remains in the digestional canal. Thus the blood takes up less fat which leads to less fat deposits in the body. The body absorbs fewer calories from the fat and the cholesterol and triglyceride levels in the blood are reduced, all in one natural process.
L112 Fat Blocker is made of a special fibre-like substance derived from the shells of shrimps, crabs and ohter shellfishes. After chemical extraction the substances has got electrostatic properties and has unique fat binding properties. It has been tested by a Norwegian research laboratory. When given orally together with the food it immediately disperse into tiny particles.
These have great affinity to fat and starts binding themselves to fat particles in the stomach and upper intestines. With increasing pH in the lower intestines the binding occurs probably through precipitation and the body cannot any longer absorb the fat through the intestinal wall or dispense the into the blood stream.
The substances has been tested in clinical trials and shows a remarkable effect in reducing total cholesterol while allowing the HDL-cholesterol to increase. In one randomized double-blind study with placebo-control the weight reduction was 2.5 times better than diet alone. A preliminary review on L112 Biopolymer has been published elsewhere. When fat contents in the bowel increases, it makes the feces soft and smooth. This may be particularly positive for those who suffer from obstipation. In this unicentre trial the fat content in feces and laboratory parameters, during treatment with L112 twice daily, will be investigated.